5īut some newer clinical studies assessing vitamin D supplementation are yielding conflicting results. Vitamin D deficiency is a significant public health concern, and even populations of countries with abundant sun exposure often don’t meet target levels. The Institute of Medicine (IOM) defines vitamin D deficiency as serum levels of 25(OH)D less than 50 nmol/l (or 30 ng/ml). Today, vitamin D deficiency is increasingly recognized as a worldwide epidemic, illustrated by the fact that more than 60% of postmenopausal women have inadequate serum levels of 25(OH)D, a common marker used to assess vitamin D status. Several studies link vitamin D deficiency with a higher risk of falls and fractures. Vitamin D is a crucial cofactor for bone health, as it regulates calcium balance and directly affects the osteoblast cells responsible for bone building and bone remodeling. We call these cofactors, and they are believed not only to be critical to bone health but also to be most effective when present together in adequate amounts. 3Ĭalcium’s effects, however, depend heavily on the actions of several other vitamins and minerals, including vitamin D, magnesium, vitamin K2, and zinc. Calcium is well-known for its benefits to bone mineral density, as it is the most abundant mineral in the human body. 2 Consuming the necessary vitamins and minerals from food as well as from dietary supplements should be an important pillar of any bone-health program. This includes exercise and also diet, with evidence indicating that nutrition plays a major role in promoting skeletal health. 1Ĭombating osteoporosis is a lifelong endeavor requiring prudent lifestyle choices. Estimates suggest that by 2025, osteoporosis will be the source of three million fractures and over $25 billion in healthcare costs each year. Osteoporosis significantly increases risk of fracture, with studies suggesting that one in two women and one in four men over the age of 50 will experience a broken bone as a result.
Loss of bone density impacts 54 million Americans, putting them directly in the path of danger of developing osteoporosis.
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